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Ärztliche Fortbildung | Kurse

Kaiser, Nicole

Pruning, the elimination of excess synapses, is a phenomenon of central importance for a correct wiring of the central nervous system. Disturbance in this strictly regulated process could be the cause of  human neurological and psychiatric diseases.
Recent studies give evidence that glia cells not only play a role at removing cell debris but also may play a more active role in pruning. Our group studies mouse lines with glia cell reporter constructs as well as mice with known pruning defect to point out the role of glia cells and related signaling-cascades.

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